Hydroquinone + Tretinoin + Fluocinolone acetonide is a combination of three medicines: Hydroquinone , Tretinoin and Fluocinolone acetonide which treat melasma (dark spots on skin). Hydroquinone is a skin lightening medicine. It reduces the amount of a skin pigment (melanin) that causes darkening of skin.

Tretinoin is a form of vitamin A that helps the skin to renew itself more quickly. Fluocinolone acetonide is a steroid which blocks the production of certain chemical messengers (prostaglandins) that make the skin red, swollen and itchy.